Volume 12 | Issue 10 |

 Abstract

The Durga Saptashati, a revered Hindu scripture, is rich in mythological narratives that symbolize the eternal struggle between good and evil. While traditionally viewed as a spiritual and religious text, its narratives offer profound insights into contemporary legal challenges and moral dilemmas. This article explores the relevance of Durga Saptashati in informing modern legal practices, focusing on themes of justice, retribution, and the role of law in societal transformation. The stories of Goddess Durga's battles against asuras like Mahishasura and Shumbha-Nishumbha provide valuable allegories for modern legal systems grappling with issues of justice, gender equality, and governance. Through a comparative analysis of these mythological tales and existing legal precedents, this article demonstrates how ancient wisdom can guide contemporary legal reasoning, offering new perspectives on accountability, restorative justice, and the balance between power and morality. The article further integrates legal maxims and judicial interpretations to illustrate how ancient narratives can bridge the gap between morality and law, encouraging a more nuanced approach to legal challenges. Through this article the researcher weaves together mythological narratives and legal precedents, demonstrating how ancient wisdom from the Durga Saptashati can inform and enrich modern legal thought.

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Legal Precedents, Justice, Gender Equality, Moral Dilemmas etc

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XRD analysis, FTIR analysis ,FESEM analysis, TEM analysis, HRTEM analysis, Seebeck coefficient and Thermoelectric power.

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Prof.N.Subbureediar is a great scholar and Writer. He was born on agriculural family in Prakambi village in Tamilnadu. He lost his father at young age. He studied from school and collge with the help of his mother. He has also written boolks on Tamil Lterature, Science, Religion. The purpose of the artilce is to reveal the establishment of the department of Tami Sri Venkateswara University, Andhra Pradesh, India. Through his effort, Post graduate students and many researcher have developed. His rare service for Tamil Language with out money or fame.

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Professor N Subbureddiyaar Life and Works

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Pharmacovigilance (PV) plays a pivotal role in ensuring drug safety by identifying, assessing, and preventing adverse drug reactions (ADRs) and other medication-related problems. This review aims to explore the evolving landscape of pharmacovigilance, highlighting key aspects such as ADR detection, the role of technology, post-marketing surveillance, and future challenges. The incorporation of artificial intelligence (AI) and machine learning (ML) into PV systems offers promising advancements in signal detection, case intake, and data mining. These technologies enable more efficient management of vast data sets, potentially improving patient safety outcomes. However, challenges persist, including underreporting, data quality, and the complexity of analyzing extensive PV data. Furthermore, global regulatory disparities and the need for a standardized approach remain key obstacles in realizing the full potential of AI in pharmacovigilance. This review discusses the benefits, current challenges, and future opportunities of PV technologies, proposing a more integrated approach for enhancing drug safety.

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Pharmacovigilance, Signal Detection, Machine Learning, Artificial Intelligence, Adverse Drug Reaction.

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Vigna mungo, Black gram, salt stress, Ascorbic acid

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Atrial fibrillation, or AF, is a frequent cardiac rhythm instability, particularly prevalent in the elderly population, with a global impact on millions. Existing treatments for AF face challenges such as limited efficacy and recurrence. Obesity significantly increases the risk of AF and associated cardiovascular complications, influenced by factors such as hypertension, diabetes, and sleep apnea. Understanding the pathophysiological links between obesity and Atrial fibrillation, including oxidative stress, fibrosis, and inflammation, is crucial. Biomarkers such as greater sensitivity troponin, C-reactive protein (CRP), natriuretic peptides (BNP, NT-proBNP), and microRNAs (miRNAs) play a crucial part in predicting also managing AF, particularly in obese patients. These biomarkers offer insights into myocardial stress and remodelling, aiding in early risk stratification and personalized treatment strategies. Current evidence suggests that elevated levels of NT-proBNP and hs-TnT are significant predictors of adverse outcomes in AF patients, emphasizing the need for aggressive management in high-risk groups. Incorporating biomarkers into AF management protocols can enhance the precision of treatment decisions, potentially reducing morbidity and mortality. Lifestyle modifications, rhythm control, antiarrhythmic drugs, and anti-inflammatory treatments are critical in managing AF in obese patients. Further research is essential to optimize the use of cardiac strain biomarkers in clinical settings, advancing towards more effective and individualized approaches for preventing and managing AF in obese populations.

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Atrial Fibrillation (AF), Obesity, Biomarkers, Risk Stratification, Inflammation

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INTRODUCTION: Neurological diseases significantly impact global mortality and disability, especially in the elderly due to age-related changes in neurochemistry and drug metabolism. Drug- induced neurological disorders (DIND) result from adverse medication effects, with the elderly at higher risk due to polypharmacy and overlapping symptoms with age-related conditions. Common manifestations include movement disorders, falls, seizures, and delirium associated with various medication classes such as dopamine receptor blockers, antithrombotic, and antidepressants. AIM: To evaluate the prevalence of drug-induced neurological disorders in elderly patients. OBJECTIVES: The study aims to assess drug-induced neurological disorders' prevalence and impact in geriatric patients, identify common ADRs linked with CNS drugs, manage related ADRs, and improve patient education on effective ADR management. METHODS: A prospective observational study in a tertiary care hospital collected data on geriatric inpatients, including demographics, causative drugs, side effects, and ADR analysis using the Naranjo scale. RESULTS: Among 60 patients, 17 experienced ADRs, with higher prevalence in females (65%) and the 60-70 age group. General medicine saw the most ADRs (37%), primarily due to anticonvulsants causing hyponatremia and sleep deprivation. 47% of drugs were withdrawn, with a 35% patient recovery rate. CONCLUSIONS: High ADR prevalence in general medicine necessitates early detection and management. Focus on high-risk patients and pharmacist-led education can improve outcomes. Longer-term studies are recommended for better ADR understanding. KEY WORDS: Drug- induced neurological disorders, elderly patients, adverse drug reactions, polypharmacy, cognitive impairment.

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Drug- induced neurological disorders, elderly patients, adverse drug reactions, polypharmacy, cognitive impairment.

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This paper, explores how Bhasa employs rhetorical strategies to engage with ethical dilemmas in his play Madhyamavyayoga. As a prominent dramatist in classical Sanskrit literature, Bhasa uses rhetoric not only to advance the narrative but also to probe deeper moral questions surrounding duty, justice, and power. By closely examining key dialogues, the paper reveals how rhetorical techniques such as appeals to pathos, ethos, and logos are employed to highlight the moral conflicts faced by the characters, particularly Bhima, the middle Pandava brother. Bhasa skillfully uses rhetoric to underscore the tension between personal duty and broader ethical responsibilities, particularly in the context of familial bonds and the morality of war. The characters in the play are not static embodiments of virtue or vice but are positioned in morally complex situations, where their choices invite reflection on the ethical consequences of their actions. Through persuasive exchanges, the characters' words become a medium for moral introspection, allowing the audience to grapple with the ethical dilemmas they face. The paper argues that Bhasa's use of rhetoric serves as a powerful tool for engaging with philosophical and ethical concerns, making Madhyamavyayoga not just a dramatic work but a profound reflection on the human condition. This analysis positions Bhasa's work within the broader tradition of classical Sanskrit drama, where rhetoric often intersects with philosophical discourse, offering valuable insights into both historical and contemporary discussions of ethics. Ultimately, the study highlights how Bhasa's interplay of rhetoric and ethics in Madhyamavyayoga enhances the dramatic depth of the play and reinforces its timeless relevance in moral discourse.

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Rhetoric, Ethics, Dharma, Kshatriya code, Sacrifice, Moral conflict, Ancient Indian theatre, Philosophical themes, Duty and honour, Familial bonds, Dialogue and irony, Classical Indian literature, Moral philosophy

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This paper focuses on the trajectory planning for the Fanuc S-430iW industrial robot, a 6-axis robotic arm used in heavy-duty industries. This robot is highly efficient and accurate. For tasks that require greater precision, it is critical to form straight-line motion. The tasks include additive manufacturing, material handling, assembly, etc. These tasks have to be performed in the shortest time. Trajectory planning ensures the robot's smooth motion and avoids any unexpected accidents. The work produces trajectory planning for a straight line in 3D space, i.e., the shortest path between two points. The trajectory planning is carried out by deriving a quintic path equation for X, Y, and Z using the initial and final points of the trajectory and constraints. The quintic path is used to determine the position, velocity, and acceleration. Then, the variation in the joint variables for the path is determined by inverse kinematics for the time-space, position, and dimensions specified. The forward and inverse kinematics are employed in calculating joint variables along the path. The output shows the robot's smooth motion along the path. The velocity along all three axes increases and decreases smoothly. The advantages of the robot lie in the fact that it can be used for various applications. Execution and cycle time are important to increase production efficiency.

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Forward and inverse kinematics, Fanuc S-430iW, trajectory planning, additive manufacturing, precision, straight line path

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India and the US have a long-standing defence relationship that has grown in depth over some time. However, the relationship had not yet attained the level of strategic partnership in the real sense. This scenario will likely change with the signing of the Security of Supply Arrangements (SOSAs). This agreement reflects the coming of age of the partnership between the two countries. By giving a reciprocal opportunity for preferential sourcing of military supplies, the agreement lays the edifice for deeper collaboration in future. The present paper looks at the past, present and future of SOSA in the context of a fledging Indo-US relationship.

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Security of Supply Arrangements (SOSAs), Indo-US relations, Reciprocal Defence Procurement Agreement

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